The esteemed 20th annual TIME100 Gala, a celebration of the world's most influential individuals, was enlivened by the comedic stylings of Nikki Glaser. Taking the stage at Jazz at Lincoln Center in New York City, Glaser, known for her candid humor, engaged the star-studded audience with a series of playful jabs. Her targets included a diverse group of personalities such as Katy Perry, Hailey Bieber, Victoria Beckham, MrBeast, and Kate Hudson, demonstrating her fearless approach to celebrity comedy while also poking fun at the TIME organization itself.

Throughout the evening, Glaser delivered a variety of memorable quips that resonated with the attendees. She humorously acknowledged the gala's unique standing, quipping about it being 'the one list you actually want to be on this year.' Her comedic observations extended to MrBeast, jokingly suggesting he might turn the gala into one of his signature challenges, and she offered a witty description of singer-songwriter Noah Kahan, likening his appearance to a nostalgic figure from a past concert. Glaser also humorously touched upon Hailey Bieber's influence in the beauty industry, the perpetual elegance of Kate Hudson, and the famously composed demeanor of Victoria Beckham, eliciting chuckles from the distinguished guests. She even playfully included Gayle King, referencing a past encounter with Katy Perry in space in a clever twist.

Beyond the comedic interlude, the gala featured captivating musical performances by Luke Combs and Coco Jones. The event also included heartfelt tributes from various honorees, such as Oscar-winning actress Zoe Saldaña, Olympic snowboarder Chloe Kim, and television personality Alan Cumming. The evening was further highlighted by remarks from TIME's chief executive officer, Jessica Sibley, and editor-in-chief, Sam Jacobs, underscoring the significance of recognizing individuals who have made substantial impacts globally. The blend of humor and recognition created an unforgettable night, celebrating influence and achievement in a truly engaging manner.